EVOLVING MARINE BIOMIMETICS FOR REGENERATIVE DENTISTRY

Evolving Marine Biomimetics for Regenerative Dentistry

New products that help make human tissue and organ regeneration more effective are in high demand and include materials, structures and substrates that drive cell-to-tissue transformations, orchestrate anatomical assembly and tissue integration with biology.Marine organisms are exemplary bioresources that have extensive possibilities in supporting

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Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors

Abstract Background Poly (ADP-Ribose) polymerase inhibitors are approved for treatment of tumors with BRCA1/2 and other homologous recombination repair (HRR) mutations.However, clinical responses are often not durable and treatment may be detrimental in advanced cancer due to excessive toxicities.Thus we are seeking alternative therapeutics to enha

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